NCEF-S 1500

Arion Healthcare brings you NCEF-S 1500 Injection, a powerful broad-spectrum antibiotic combination that delivers comprehensive antibacterial coverage against a wide range of pathogenic microorganisms. This sterile injectable formulation combines Ceftriaxone (1000mg) and Sulbactam (500mg) to provide healthcare professionals with a reliable treatment option for moderate to severe bacterial infections.

Ceftriaxone, a third-generation cephalosporin antibiotic, works by inhibiting bacterial cell wall synthesis and effectively killing susceptible bacteria. Meanwhile, Sulbactam serves as a beta-lactamase inhibitor that protects Ceftriaxone from enzymatic degradation by beta-lactamase-producing bacteria. Consequently, this synergistic combination extends the antimicrobial spectrum and significantly enhances efficacy against resistant strains.

The formulation offers excellent flexibility for clinical settings because healthcare providers can administer it via both intravenous (IV) and intramuscular (IM) routes. Each vial contains sterile Ceftriaxone IP equivalent to anhydrous Ceftriaxone 1000mg and Sulbactam Sodium IP equivalent to Sulbactam 500mg. Furthermore, this fixed-dose combination ensures accurate dosing and convenient administration in hospitals and clinics.

Key Benefits

• Dual-action antibacterial – Combines Ceftriaxone and Sulbactam for enhanced antimicrobial activity

• Broad-spectrum coverage – Effective against Gram-positive and Gram-negative bacteria

• Resistance prevention – Sulbactam inhibits beta-lactamase enzymes to prevent antibiotic degradation

• Versatile administration – Can be administered via IV or IM routes

• High potency – 1500mg strength provides powerful therapeutic effect

• GMP certified – Manufactured under strict quality standards by Arion Healthcare

• Hospital-grade formulation – Suitable for severe and complicated infections

Indications

NCEF-S 1500 Injection is indicated for the treatment of the following bacterial infections:

• Respiratory tract infections – Pneumonia, bronchitis, lung abscess

• Urinary tract infections – Pyelonephritis, cystitis, urethritis

• Skin and soft tissue infections – Cellulitis, abscesses, wound infections

• Intra-abdominal infections – Peritonitis, biliary tract infections

• Bone and joint infections – Osteomyelitis, septic arthritis

• Gynecological infections – Pelvic inflammatory disease

• Sepsis – Systemic bacterial infections

• Surgical prophylaxis – Prevention of postoperative infections

• Neonatal infections – Under medical supervision

• Meningitis – Bacterial meningitis treatment

Side Effects

While NCEF-S 1500 is generally well-tolerated, some patients may experience:

Common Side Effects

• Pain at the injection site

• Diarrhea

• Nausea

• Vomiting

• Rash or skin irritation

• Elevated liver enzymes

Less Common Side Effects

• Allergic reactions (rash, itching, urticaria)

• Headache

• Dizziness

• Eosinophilia

• Thrombocytosis or leukopenia

• Increased creatinine levels

Frequently Asked Questions 

Q1: What is NCEF-S 1500 Injection used for?
NCEF-S 1500 Injection is a combination antibiotic used to treat moderate to severe bacterial infections, including respiratory, urinary tract, skin, bone, and intra-abdominal infections.

Q2: How is NCEF-S 1500 Injection administered?
This injection can be given either intramuscularly (into the muscle) or intravenously (into the vein) as directed by your physician.

Q3: What should I do if I miss a dose?
Take the missed dose as soon as you remember. If it’s close to the next scheduled dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Q4: Can NCEF-S 1500 be used during pregnancy?
Use during pregnancy should only be considered if clearly needed and prescribed by a qualified medical practitioner. Consult your doctor for individual assessment.

Q5: Is NCEF-S 1500 safe for patients with penicillin allergy?
Patients with penicillin allergy may have cross-sensitivity to cephalosporins. Inform your physician about any known allergies before administration.